What THC Does to the Brain?

Ever wondered what exactly makes you feel “high” after consuming cannabis? THC, also known as Tetrahydrocannabinol, is a compound in the cannabis plant that can transform your mood, senses, perspective, energy levels, and even your cravings. By exploring how THC impacts the brain, users can better understand how to use cannabis for both recreational and medicinal purposes.

What is THC?

Cannabis has over 480 compounds in the plant, with only around 66 of those compounds being cannabinoids. The most commonly known cannabinoid is Tetrahydrocannabinol which serves as the main chemical compound (or cannabinoid) found in the cannabis plant and is the primary psychoactive ingredient. 

On average, THC content in flower ranges from 15%-25% with some strains boasting 35%. The higher the THC content, the higher the user will feel. 

How Does THC Affect The Brain?

The body has a complex signaling system in the body called the endocannabinoid system. Endocannabinoids and receptors can be found throughout the body and regulates and controls executive and bodily functions. THC interacts with the endocannabinoid system and temporarily produces a “high”. The THC temporarily alters everything from the user’s perception, coordination, memory, pleasure, concentration, and even appetite. 

The THC interacts with brain receptors and leads to changes in day-to-day function. Below you can see a graph from the American Psychological Association, outlining the various ways THC affects the brain. 

• Hypothamalus: The hypothalamus controls appetite, hormonal levels, and sexual behavior. THC releases dopamine in the hypothalamus which increases pleasure. This is why users often experience the “munchies” (increased appetite) or have a heightened sex drive. 
• Basal Ganglia: The basal ganglia affects motor control. THC temporarily alters the basal ganglia and can lead to changes in motor control, including a “body high” or simply moving slower than normal.
• Hippocampus: The hippocampus is critical when it comes to memory formation and spatial awareness. THC temporarily alters the hippocampus, which often leads to short-term memory loss and difficulty remembering new information. 
• Neocortex: The neocortex is critical when it comes to users’ perception and sensory experiences. THC alters the neocortex, which is why sounds, colors, music, and taste can feel enhanced.
• Amygdala: The amygdala controls emotions, anxiety, and fear. THC can reduce or increase these feelings. Oftentimes lower doses lead to relaxation, while higher doses might cause paranoia and anxiety.
• Cerebellum: The Cerebellum regulates coordination. THC can impair balance and physical coordination, which is why activities like driving or operating heavy machinery are incredibly dangerous while high. 
• Brain Stem and Spinal Cord: The brain stem and spinal cord impact bodily functions, pain sensation, and vomiting reflex. THC reduces pain and can suppress nausea, which is why cannabis is often used medicinally for patients with chronic pain or even individuals going through chemotherapy. 
• Ventral Striatum: The ventral striatum affects the reward system and motivation. THC can stimulate the ventral striatum and cause users to feel more motivated or enjoy mundane activities more. 

Credit: American Psychological Association

Where Can I Purchase Legal Cannabis?

It is critical to purchase cannabis from a legalized and reputable dispensary or delivery service. 

Looking to try cannabis or CBD and have it delivered right to your door? Visit us at www.trydoobie.com to place an order. Need a little extra help? Chat with the Doobie Concierge team on the website for any questions you may have.

Disclaimer: The content provided in this article is for informational purposes only. Please consume cannabis responsibly and follow all local laws and regulations.

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